Subject Area and Research Team: VII. Physical and clinical aspects of radiotherapy
Research topics
1. Biology
– Impact of total body radiotherapy (TBI) on regulatory T-cells
2. Physical aspects
- Verification of absorbed dose and patient position during breath hold radiotherapy (RT)
- In vivo dosimetry during TBI
- Dose distribution of brachytherapy in advanced cervical cancer.
3. Clinical aspects
- Long-term results of RT in locally advanced and oligometastatic non-small cell lung cancer
- Long-term results of concurrent radiochemotherapy in head and neck cancer
- Prevention and treatment of RT-induced osteonecrosis of the jaw
- Radiological and radiomics features of oropharyngeal cancers with nodal metastases
- Esophagus sparing RT techniques in non-small cell lung cancer
- Reduction of RT dose to the heart in breast cancer patients
- Impact of stereotactic RT on lung parenchyma
Coordinators
| Coordinator #1 | Coordinator #2 | |
|---|---|---|
| Name and surname |  |
 |
| Academic degree | Dr. Habil. | Ph.D. Eng. |
| Employment unit | Department of Oncology and Radiotherapy | Department of Oncology and Radiotherapy Faculty of Mathematics, Physics and Computer Science, Institute of Experimental Physics, Department of Acoustics and Nuclear Physics – University Of Gdańsk |
| abadzio@gumed.edu.pl | j.kaminska@gumed.edu.pl | |
| Phone number | +48 58 349 45 10 | +48 58 349 22 81 |
Research Team: VII. Physical and clinical aspects of radiotherapy
Team Members: VII. Physical and clinical aspects of radiotherapy (165 KB)Feel free to contact one of our coordinators to join our Research Team.
Key current projects
1. Impact of low dose total body radiotherapy on Treg function
2. EPR dosimetry in deep-inspiration breath hold radiotherapy
3. Contralateral oesophagus sparing technique and predictive models for radiation-induced esophagitis in non-small cell lung cancer patients receiving concurrent chemoradiotherapy.
4. Radiological and radiomics features of oropharyngeal cancers with nodal metastases
5. Reduction of the dose to left coronary vessel and heart in proton irradiation and photon deep breath hold radiotherapy in breast cancer patients
International cooperation
| Foreign partner (unit name) | Principal investigator(s) | Area of cooperation | |
|---|---|---|---|
| 1. | Laboratory of Pathology, National Cancer Institute (NCI), Bethesda, Maryland, USA | Jerzy Lasota | Clinical aspects of radiotherapy – outcome of treatment and side effects of radiotherapy |
| 2. | Division of Radiotherapy, IEO European Institute of Oncology, IRCCS, Milan, Italy | Barbara Alicja Jereczek-Fossa | Clinical aspects of radiotherapy – outcome of treatment and side effects of radiotherapy |
Key publications
1. Christodoulou M, Blackhall F, Mistry H, Leylek A, Knegjens , Remouchamps V, Martel-Lafay Farré N, Zwitter M , Lerouge D, Pourel N, Janicot H, Scherpereel A, Tissing-Tan C, Peignaux K, Geets X, Konopa K , Faivre-Finn C. Compliance and Outcome of Elderly Patients Treated in the Concurrent Once-Daily Versus Twice-Daily Radiotherapy (CONVERT). Trial. J Thorac Oncol 2019; vol. 14: p. 63-71.
2. Cremonesi M, Garibaldi C, Timmerman R, Ferrari M, Ronchi S, Grana CM, Travaini L, Gilardi L, Starzyńska A, Ciardo D, Orecchia R, Jereczek-Fossa BA, Leonardi MC. Interim 18F-FDG-PET/CT during chemo-radiotherapy in the management of oesophageal cancer patients. A systematic review. Radiother Oncol 2017; vol. 125: p. 200-212.
3. Isaksson LJ, Pepa M, Zaffaroni M, Marvaso G, Alterio D, Volpe S, Corrao G, Augugliaro M, Starzyńska A, Leonardi MC, Orecchia R, Jereczek-Fossa BA. Machine learning-based models for prediction of toxicity outcomes in radiotherapy. Front. Oncol. 2020; vol. 10: p. 1-14.
4. Guckenberger M, Belka C, Bezjak A, Bradley J, Daly ME, DeRuysscher D, Dziadziuszko R, Faivre-Finn C, Flentje M, Gore E, Higgins KA, Iyengar P, Kavanagh BD, Kumar S, Le Pechoux C, Lievens Y, Lindberg K, McDonald F, Ramella S, Rengan R, Ricardi U, Rimner A, Rodrigues GB, Schild SE, Senan S, Simone CB 2nd, Slotman BJ, Stuschke M, Videtic G, Widder J, Yom SS, Palma D. Practice Recommendations for Lung Cancer Radiotherapy During the COVID-19 Pandemic: An ESTRO-ASTRO Consensus Statement. Int J Radiat Oncol Biol Phys. 2020; vol. 107(4): p. 631-640.
5. Nowak J, Pawłowska E. Technical note: an algorithm and software for conversion of radiotherapy contour-sequence data to ready-to-print 3D structures. Med. Phys. 2019; vol. 46(4): p. 1829-1832.
6. Zemanova M, Jakopovic M, Stanic K, Łazar-Poniatowska M, Vrankar M, Rusu P, Ciuleanu T, Radosavljevic D, Bogos K, Nawrocki S. Treatment patterns and real-world evidence for stage III non-small cell lung cancer in Central and Eastern Europe. Radiol Oncol 2020; vol. 54(4): p. 447-454.