Area and Research Team: VIII. Sleep medicine
Research topics
1. Chemosensitivity, and blood pressure control in patients with obstructive sleep apnea
2. Sleep disordered breathing in diabetic patients
3. Microcirculation alterations in sleep apnea
4.Blood pressure control after CPAP commencement – role of diurnal activity
5.Microcirculation and large arteries’ function in patients receiving centrally-acting drugs
6. Sleep apnea in rare diseases pediatric populations
Coordinators
| Coordinator #1 | Coordinator #2 | |
|---|---|---|
| Name and surname |  |
 |
| Academic degree | Dr. Habil. | Ph.D. |
| Employment unit | Department of Hypertension and Diabetology | Department of Psychiatry |
| Polish Platform of Medical Research | Dr. Habil. Jacek Wolf | Karol Grabowski, Ph.D. |
| jacek.wolf@gumed.edu.pl | karol.grabowski@gumed.edu.pl | |
| Phone number | +48 58 34 925 27 | +48 58 34 917 97 |
photos Paweł Sudara/MUG
Research Team: VIII. Sleep medicine
Team Members: VIII. Sleep medicine (154 KB)Feel free to contact one of our coordinators to join our Research Team.
Key current projects
1. Autonomic control differences with relation to familial history of sleep apnea
2. Epidemiological assessment and prognostinc value of sleep disordered breathing in diabetic patients
3. Non-invasive assessment of microcirculation of the brain of patients receiving cpap-therapy
4. CPAP blood lowering effect – role of rarely reported changes in nocturnal and diurnal physical activity
5. Role of anti-depressive and hypnotic novel drugs in diurnal cardiovascular control
International cooperation
| Foreign partner (unit name) | Principal investigator(s) | Area of cooperation | |
|---|---|---|---|
| 1. | Cardiovascular Facility and the Sleep Facility at Mayo Clinic’s Center | PROF. V.K. SOMERS | Cardiovascular control with relation to sleep disordered breathing |
| 2. | UNIVERSITY OF GENOA, DIVISION OF NEUROSCIENCE, GENOA, ITALY | Chiarra Robba | Subarachnoid pulsatility in sleep apnea |
| 3. | Cambridge University Hospital, Brain Physics Laboratory, Division of Neurosurgery, Department of Clinical Neurosciences, Cambridge, United Kingdom | Prof. Marek Czosnyka | Subarachnoid pulsatility in sleep apnea |
| 4. | DEPARTMENT OF CARDIOVASCULAR, NEURAL AND METABOLIC SCIENCES AT ST. LUKE HOSPITAL, ISTITUTO AUXOLOGICO ITALIANO. UNIVERSITY OF MILANO-BICOCCA | PROF. GIANFRANCO PARATI | Cardiovascular control with relation to sleep disordered breathing |
| 5. | Department of Cardiology, Almazov National Medical Research Centre, St Petersburg, Russia | Lyudmila Korostovtseva | Cardiovascular control in sleep disordered breathing |
Key publications
1. J. Wolf, J. Drozdowski, K. Czechowicz, P. J. Winklewski, E. Jassem, T. Kara, V.K. Somers, K. Narkiewicz. Effect of beta-blocker therapy on heart rate response in patients with hypertension and newly-diagnosed untreated obstructive sleep apnea syndrome. Int. J. Cardiol. 2016; vol. 202, s. 67-72
2. J. Wolf, T. Dereziński (joint 1st author), A. Szyndler, K. Narkiewicz. Prevalence and characteristics of OSAFED syndrome in atrial fibrillation primary care patients. Kardiol. Pol. 2017;75:432-438.
3. M. Wszedybyl-Winklewska (joint 1st author), J. Wolf (joint 1st author), A. Szarmach, P. Winklewski, E. Szurowska, K. Narkiewicz. Central sympathetic nervous system reinforcement in obstructive sleep apnoea. Sleep Med. Rev. 2018;39,143-154.
4. Current understanding of the effects of inspiratory resistance on the interactions between systemic blood pressure, cerebral perfusion, intracranial pressure, and cerebrospinal fluid dynamics. Winklewski PJ, Wolf J, Gruszecki M, Wszedybyl-Winklewska M, Narkiewicz K. J Appl Physiol (1985). 2019 Nov 1;127(5):1206-1214
5. Impact of slow breathing on the blood pressure and subarachnoid space width oscillations in humans. Nuckowska MK, Gruszecki M, Kot J, Wolf J, Guminski W, Frydrychowski AF, Wtorek J, Narkiewicz K, Winklewski PJ. Sci Rep. 2019 Apr 17;9(1):6232.