Area and Research Team: VI. Heart rhythm and sudden cardiac death
Research topics
1. Non-invasive prognostic risk factors of malignant arrhythmias and neurogenic syncope in patients with normal heart, left and right ventricle dysfunction
2. Risk factors of ventricular arrhythmias, myocardial dysfunction, and prognosis in patients with hereditary cardiomyopathies, channelopathies, and arrhythmogenic mitral valve prolapse
3. Combined analysis of patients with atrial fibrillation, including patients with acute myocardial infarction and patients after cardio-surgery operations, with particular attention to metabolomic mechanisms of arrhythmia
4. Subcutaneous cardioverter-defibrillator in sudden cardiac death prevention
5. Complications of invasive electrotherapy – prophylaxis and treatment
Key current projects
1. Polish S-ICD Registry
2. Malignant mitral prolapse – risk factors and prognosis
3. Unmarked and targeted metabolomics analysis in atrial fibrillation assessment using analytical techniques coupled with spectrometry and advanced bioinformatics methods
4. Natural History and Risk Stratification in Andersen-Tawil Syndrome Type 1.
5. The impact of the multisite pacing of the left ventricle on clinical and echocardiographic parameters in patients with CRT-D
Coordinators
| Coordinator #1 | Coordinator #2 | |
|---|---|---|
| Name and surname |  |
 |
| Academic degree | Prof. Dr. Habil. | Dr. Habil. |
| Employment unit | Department of Cardiology and Electrotherapy | Department of Cardiology and Electrotherapy |
| Polish Platform of Medical Research | Prof. Dr. Habil. Ludmiła Daniłowicz-Szymanowicz | Dr. Habil. Maciej Kempa |
| ludmila.danilowicz-szymanowicz@gumed.edu.pl | maciej.kempa@gumed.edu.pl | |
| Phone number | +48 58 34 939 10 | +48 58 34 939 10 |
photos Paweł Sudara/MUG
Research Team: VI. Heart rhythm and sudden cardiac death
Team Members: VI. Heart rhythm and sudden cardiac death (178 KB)Feel free to contact one of our coordinators to join our Research Team.
Key grants
| Funding agency/grant numer | Title of the project | Years | |
|---|---|---|---|
| 1. | grant Boston Scietific | Polish S-ICD Registry | 2021-2022 |
| 2. | Ministerstwo zdrowia / POWR.05.04.00-IP.05-00-006/18 | Podniesienie jakości wysokospecjalistycznego kształcenia podyplomowego w zakresie kardiologii”, współfinansowanego ze środków Europejskiego Funduszu Społecznego w ramach Programu Operacyjnego Wiedza Edukacja Rozwój na lata 2014-2020 | 2019-2022 |
| 3. | Boehringer Ingelheim grant | Assessment of the markers of myocardial damage in patients with heart failure with moderately reduced left ventricular ejection fraction of ischemic origin | 2018 |
| 4. | Bayer grant | Unmarked and targeted metabolomics analysis in atrial fibrillation assessment using analytical techniques coupled with spectrometry and advanced bioinformatics methods | 2017 |
International cooperation
| Foreign partner (unit name) | Principal investigator(s) | Area of cooperation | |
|---|---|---|---|
| 1. | Cardiologia Molecolare Fondazione Salvatore Maugeri, Pavia, Italy | Prof. Sylvia Priori | Risk Stratification in Andersen-Tawil Syndrome Type 1 |
| 2. | Cardiology Department, S. Cuore Hospital, Negrar, Verona, Italy | Ludmila Danilowicz-Szymanowicz/Giulio Molon | Microvolt T-wave alternans as a non-invasive predictor of ventricular arrhythmias |
| 3. | Klinika za Bolesti Srca i Krvnih Zila, Zagreb, Croatia | Ludmila Danilowicz-Szymanowicz/Mislav Puljevic | Microvolt T-wave alternans as a non-invasive predictor of ventricular arrhythmias |
| 4. | Laboratory Blueprint Genetics, Finland | Joanna Kwiatkowska | Heart Rhythm and Sudden Cardiac Death in Children |
| 5. | Department of Biomedical Engineering, Fondazione „Salvatore Maugeri”, IRCCS, Istituto Scientifico di Montescano, Montescano, Pavia, Italy | Grzegorz Raczak/Gian Domenico Pinna | Autonomic Tone in arrhythmias |
Key publications
1. Mazzanti A, Guz D, Trancuccio A, Pagan E, Kukavica D, Chargeishvili T, Olivetti N, Biernacka EK, Sacilotto L, Sarquella-Brugada G, Campuzano O, Nof E, Anastasakis A, Sansone VA, Jimenez-Jaimez J, Cruz F, Sánchez-Quiñones J, Hernandez-Afonso J, Fuentes ME, Średniawa B, Garoufi A, Andršová I, Izquierdo M, Marinov R, Danon A, Expósito-García V, Garcia-Fernandez A, Muñoz-Esparza C, Ortíz M, Zienciuk-Krajka A, Tavazzani E, Monteforte N, Bloise R, Marino M, Memmi M, Napolitano C, Zorio E, Monserrat L, Bagnardi V, Priori SG. Natural History and Risk Stratification in Andersen-Tawil Syndrome Type 1.;J Am Coll Cardiol; 2020; 75 (15): 1772-1784
2. Puljevic M., Daniłowicz-Szymanowicz L., Molon G., Puljevic D., Raczak G., Canali G., Velagic V., Pezo-Nikolic B., Milicic D. TWARMI pilot trial: The value and optimal criteria of microvolt T-wave alternans in the diagnosis of reversible myocardial ischemia in patients without structural cardiac disease; Ann. Noninvas. Electrocardiol. 2019; 2019; 1. vol. 24, nr 2, 1-8
3. Segreti L, Rinaldi CA, Claridge S, Svendsen JH, Blomstrom-Lundqvist C, Auricchio A, Butter C, Dagres N, Deharo JC, Maggioni AP, Kutarski A, Kennergren C, Laroche C, Kempa M, Magnani A, Casteigt B, Bongiorni MG; ELECTRa Investigators. Procedural outcomes associated with transvenous lead extraction in patients with abandoned leads: an ESC-EHRA ELECTRa (European Lead Extraction ConTRolled) Registry Sub-Analyses; Europace; 2019; 21 (4): 645-654
4. Deutsch K, Ciurzyński M, Śledź J, Zienciuk-Krajka A, Mazij M, Ludwik B, Stec P, Wileczek A, Pruszczyk P, Stec S; Association between the geographic region and the risk of familial atrioventricular nodal reentrant tachycardia in the Polish population; Pol Arch Intern Med.; 2021; 30;131(11):16099
5. Kempa M, Przybylski A, Budrejko S, Fabiszak T, Lewandowski M, Kaczmarek K, Tajstra M, Grabowski M, Mitkowski P, Tubek S, Jędrzejczyk-Patej E, Lenarczyk R, Jagielski D, Romanek J, Rydlewska A, Orski Z, Zakrzewska-Koperska J, Filipecki A, Janowski M, Potpara T, Boveda S. Utilization of Sucutaneous Cardioverter-Defibrillator in Poland and Europe – Comparison of the Results of Multi-Center Registeries; Int J Environ Res Public Health; 2021; 2021, 5;18(13):7178