Subject Area and Research Team: IV. Heart failure and transplantation

Subject Area and Research Team: IV. Heart failure and transplantation

Research topics

1. Non-invasive assessment of acute heart rejection

2. Tako-tsubo cardiomyopathy

3. Heart failure in children and young adults with heart disease – current diagnostic and therapeutic possibilities

4. Heart rhythm analyses in heart transplant recipients

5. Experimental models of heart failure with preserved ejection fraction


Coordinator #1 Coordinator #2
Name and surname
Michał Bohdan
Piotr Siondalski
Academic degree Ph.D. Dr. Habil.
Employment unit Department of Cardiac and Vascular Surgery, Medical University of Gdańsk Department of Cardiac and Vascular Surgery, Medical University of Gdańsk
Polish Platform of Medical Research Michał Bohdan, Ph.D. Dr. Habil. Piotr Siondalski
Phone number +48 58 34 925 00 +48 58 58 442 00

photos Paweł Sudara/MUG

Research Team: IV. Heart failure and transplantation

Team Members: IV. Heart failure and transplantation (166 KB)

Feel free to contact one of our coordinators to join our Research Team.

Key current projects

1. Less invasive methods of acute heart rejection assessment by using liquid biopsies

2. Tako-tsubo cardiomyopathy: clinical characteristics and novel therapeutic methods

3. Heart rhythm analyses in patients after heart transplantation

4. Congenital heart disease and heart failure

5. Noninvasive prognostic risk factors of major cardiovascular events in patients with heart failure with reduced and moderately-reduced left ventricular ejection fraction with particular attention to speckle tracking echocardiography, autonomic nervous tone, microvolt T-wave alternans, and mi-RNA testing

Key grants

Funding agency/grant numer Title of the project Years
1. Boehringer Ingelheim grant Assessment of the markers of myocardial damage in patients with heart failure with moderately reduced left ventricular ejection fraction of ischemic origin 2018

International cooperation

Foreign partner (unit name) Principal investigator(s) Area of cooperation
1. University of Zurich Miłosz Jaguszewski International Tako-tsubo registry (INTER-TAK)
2. Leiden University Medical Center Dept. Cell and Chemical Biology Joanna Kwiatkowska Database of Pulmonary Hypertension in the Polish Population (BNP.PL). Research: patient lung and RV tissue (paraffin/frozen) and plasma samples with the diagnosis IPAH, HPAH, PAH-CHD, etc. Prof. Anton vonk Noordegraaf, Prof. Harm Jan Bogaard and Prof. Rolf Berger in Amsterdam/Groningen.

Key publications

1. Napp LC, Cammann VL, Jaguszewski Jet et al. Coexistence and outcome of coronary artery disease in Takotsubo syndrome. European Heart Journal, ehaa210, (IF=22.673)

2. Kwiatkowska J, Zuk M, Migdal A, Kusa J, Skiba E, Zygielo K, Przetocka K, Werynski P, Banaszak P, Rzeznik-Bieniaszewska A, Surmacz R, Bobkowski W, Wojcicka-Urbanska B, Werner B, Pluzanska J, Ostrowska K, Waldoch A, Kopec G. Children and Adolescents with Pulmonary Arterial Hypertension: Baseline and Follow-up Data from the Polish Registry of Pulmonary Hypertension (BNP-PL). J. Clin. Med. 2020, 9, 1717; doi:10.3390/jcm9061717 (IF=5.6)

3. Wdowczyk J, Makowiec Danuta, Gruchała M, Wejer Dorota, Struzik Zbigniew Dynamical landscape of heart rhythm in long-term heart transplant recipients: a way to discern erratic rhythms. Front. Physiol.2018, 9: 1-16. DOI: 10.3389/fphys.2018.00274 (IF 3.201)

4. Bieńkowski M, Pęksa R, Popęda M, Kołaczkowska M, Frankiewicz A, Żaczek AJ, Gruchała M, Biernat W, Siondalski P. Liquid biopsy for minimally invasive heart transplant monitoring: a pilot study. J Clin Pathol. 2020 Aug;73(8):507-510. doi: 10.1136/jclinpath-2019-205926. Epub 2019 Dec 5. (IF 2.346)

5. Kaufmann D, Szwoch M, Kwiatkowska J, Raczak G, Daniłowicz-Szymanowicz L. Global longitudinal strain can predict heart failure exacerbation in stable outpatients with ischemic left ventricular systolic dysfunction. PLoS One. 2019;14(12):e0225829. (IF=2.740)